Greenville has been assigned to the Roxana Class 2A Volleyball Regional.
The Lady Comets are seeded seventh out of 11 teams in the sub-sectional.
They will open regional play Monday, October 25 at 6 p.m. against 10th-seeded Southwestern Piasa.
A win would place the GHS girls into a semi-final match against top-seeded Staunton at 5:30 p.m. on Tuesday, October 26.
The championship match is Thursday, October 28 at 6 p.m.
All matches will be played at Roxana.